Genetic Susceptibility, HIV Infection, and the Kidney

Kidney Disease and HIV Infection

Kidney disease in HIV-infected persons manifests in a variety of ways, including acute kidney injury (AKI), HIV-associated kidney disease, comorbid chronic kidney disease (CKD), and treatment-related kidney toxicity. The burden of CKD and end-stage renal disease (ESRD) remains high in the HIVinfected population. There are several important caveats to consider when diagnosing and managing kidney...

Kidney Involvement in HIV Infection

Human immunodeficiency virus (HIV) infection can involve various organs of the body. Kidney involvement is frequently seen during course of human immunodeficiency virus infection and it has become fourth leading condition contributing to death in acquired immunodeficiency virus (AIDS) patients after sepsis, pneumonia, and liver disease. Rao first described the presence of focal segmental glomer...

Association Between HLA Gene Polymorphism And The Genetic Susceptibility Of HIV Infection

HIV infection and kidney disease: literature review

Combination antiretroviral-therapy (cART) has improved HIV-positive patients mortality and life expectancy. On the other hand, the prevalence of comorbidities, such as cardiovascular disease, hepatic and renal disease has increased. Kidney disease is one of the main causes of morbidity and mortality, especially if accompanied by older age, diabetes, hypertension, black race and hepatitis C coin...

The kidney in HIV infection: beyond HIV-associated nephropathy.

Acute kidney injury (AKI) and chronic kidney disease (CKD) are more common in HIV-infected persons than in the general population. AKI is associated with poor health outcomes, including increased risk of heart failure, cardiovascular events, end-stage renal disease (ESRD), and mortality. The most common causes of AKI in HIV-infected persons are systemic infections and adverse drug effects. The ...